If you can come up with a way to disconnect it, and thus render it 'not present' and 'not detectable,' you will be able to proceed. You are NOT going to be able to upgrade a machine that has hardware that is recognized as incompatible with Windows 10, and that's a good thing. I've spent all day for the last 4 days trying to track down any files related to this program and HAVE HAD IT. I've tried downloading and installing the latest driver from Realtek thinking possibly the latest driver would be compatible with Windows 10. I've downloaded and used special uninstall programs. I looked in the registry under the Incompatibility App key/folder.all that's left in there is CrapCleaner and my Gateway registation folder(s). I've erased every blessed thing I could find related to this!! I've deleted keys in the Registry, deleted/disable devices in Device Manager. Message STILL pops up, now telling me to manually uninstall.

First time, I clicked the Uninstall button.

I get a pop up with 'Realtek PCEI card reader' is incompatible with Windows 10.

I managed to get it done on my laptop but my desktop installation really has me FUSTRATED! I've finally decided to upgrade from Windows 7 to 10.

Speccy windows 10 incompatable